What wildly popular Las Vegas-based indie rock band is made up of Brandon Flowers, Dave Keunin, Mark Stoermer, and Ronnie Vannucci?

Answer The Killers

The Killers achieved worldwide popularity as they evolved from a dance-rock band to pioneers of alternative rock music. With a blend of 1980s synth-pop, the band's debut Hot Fuss included the single "Mr. Brightside" that brought the band international success.

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