What is the name of the short-lived ancient empire that was responsible for spreading Greek culture throughout the Middle East, and stretched from southeastern Europe to the Indus River?

Answer Macedonian Empire

Alexander III (Alexander the Great) created Macedonia's Empire by conquering the Persians, and expanding Macedonia's lands to stretch beyond the Nile River and up to the Indus River all in just over a decade. This massive ancient empire began the Hellenistic Age, which spread Greek culture throughout this region. Alexander's empire would be short-lived though, because at his death in 323 BC, his generals divided the territories into their own separate empires.

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