Wayne's first leading role was as a young trapper crossing from the Mississippi River to the West on a wagon train. Name that film.

Answer The Big Trail

Raoul Walsh's The Big Trail, a 1930 film, helped launch Wayne's career as a leading man. The western epic saw Wayne as a young trapper at the head of a wagon train, heading West. Having groomed Wayne, director John Ford apparently was angry that Wayne took the role and didn't work with him for years afterward.

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