The Frank Capra-directed film adaptation of this play starred Cary Grant. It follows Mortimer, who is put in an awkward position when he finds out his sweet little aunts are straight up murdering people.
Answer Arsenic and Old Lace
Arsenic and Old Lace sees a man realizing his family is a whole other brand of crazy than he'd originally thought. When he visits with his newlywed wife, he discovers a corpse secreted away at a window seat.
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